Vol 4, No 3 (2010)

The randomized, double-blind trial was designed to evaluate rectal diclofenac in the relief of perineal pain after trauma during childbirth. Women were randomly allocated to either diclofenac (n=67) or placebo suppositories (n=66). The use of rectal nonsteroidal anti-inflammatory drug suppositories is a simple, effective and safe method of reducing the pain experienced by women following perineal trauma within the first 24 hours after childbirth.

The clinical trial included 144 patients with uterine fibromyoma scheduled for surgical treatment. All patients were randomized into three groups. One group (n=35) was assigned to general anesthesia. The second one (n=51) received spinal anesthesia, and the third one (n=54) epidural blockade was administered. Our results suggest that perioperative epidural blockade provides the most adequate anesthesia for this surgical treatment.

The clinical experience of 100 combined spinal-epidural anesthesias (CSEA), 100 epidural and 50 single-shot spinal blockades for elective cesarean section were reviewed. The CSEA included epidural catheterization following intrathecal administration of 12-15 mg of 0,5% bupivocaine. For spinal and epidural anesthesia standard technique was employed involving 12-15 mg of 0,5% bupivocaine intrathecally or 150 mg 0,75% ropivocaine epidurally. The results suggest that CSEA as have being applied in our work has no additional benefits but more rapid onset of action when compared with epidural anesthesia, and possibility of the post surgery epidural analgesia in contrast of single-shot spinal blockade.