Comparative Effectiveness of the Erector Spinae Block and Paravertebral Block in Thoracoscopic-Assisted Surgical Interventions: A single-center, prospective, randomized study



Cite item

Full Text

Abstract

BACKGROUND: Effective management of postoperative pain in thoracic surgery is a critical task, as insufficient postoperative analgesia can lead to serious complications, including atelectasis, pneumonia, and chronic pain. Despite advances in pain management techniques, uncertainty remains for the optimal analgesia technique. Paravertebral block (PVB) is considered an effective analgesic technique for video-assisted thoracoscopic surgery (VATS); however, it requires a high level of expertise and carries certain risks. In recent years, the erector spinae plane block (ESPB) has gained popularity as an alternative regional anesthesia technique, but data on its efficacy remain controversial. Further research is needed to compare the advantages and disadvantages of these methods.

AIM: To compare the analgesic efficacy of ESPB and PVB in the perioperative period following VATS wedge lung resection in patients with oncological diseases.

MATERIALS AND METHODS: A single-center prospective randomized controlled study was conducted on 45 patients aged 18–75 years who underwent VATS biopsy or wedge lung resection. Patients were randomized into two groups: ESPB (n=22) and PVB (n=23). The primary endpoints included pain intensity in the intraoperative and postoperative periods, assessed using the numerical rating scale (NRS). Pain was evaluated at rest and during coughing, along with hemodynamic changes.

RESULTS: Pain intensity according to the NRS was minimal in both groups during the first 3 hours after extubation. However, a statistically significant difference was observed from the 4th hour, with lower pain scores in the PVB group (p<0.05). Pain during coughing was also lower in the PVB group for up to 48 hours postoperatively. No significant differences in fentanyl consumption were found between the groups (p=0.72). Anesthesia execution time was shorter in the ESPB group (p<0.05). Hypotension requiring vasopressor support was more frequent in the PVB group. Despite statistically significant differences, pain scores did not exceed 4 points within 48 hours in both groups, suggesting comparable effectiveness of the two blocks for this type of surgery.

CONCLUSION: The findings indicate that ESPB and PVB provide comparable postoperative analgesia following VATS lung resection. ESPB demonstrated technical simplicity and shorter execution time, whereas PVB provided a more pronounced analgesic effect during coughing. Given the shorter execution time, ESPB may be preferable in cases where PVB is associated with a high risk of complications.

Full Text

Restricted Access

About the authors

Marat R. Akhmadullin

St. Petersburg City Clinical Oncology Dispensary, St. Petersburg, Russia; MEDSI, St. Petersburg, Russia

Email: akhmadullin.marat.rad@yandex.ru
ORCID iD: 0009-0004-6753-5066
SPIN-code: 4175-4096

anesthesiologist-resuscitation

Russian Federation, St. Petersburg, Russia; St. Petersburg, Russia

Yaroslav I. Vasiliev

St. Petersburg City Clinical Oncology Dispensary, St. Petersburg, Russia; North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia

Email: yaroslav.Vasilev@szgmu.ru
ORCID iD: 0000-0001-9758-2390
SPIN-code: 4425-9169

MD, Cand. Sci. (Medicine) , Associate Professor, Head of the Center of Anesthesiology and Intensive Care Medicine 

Russian Federation, St. Petersburg, Russia; St. Petersburg, Russia

Nadezhda G. Marova

MEDSI, St. Petersburg, Russia; North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia

Email: mnsno@mail.ru
ORCID iD: 0000-0002-5801-9594
SPIN-code: 5935-5615

Cand. Sci. (Medicine), Associate Professor

Russian Federation, St. Petersburg, Russia; St. Petersburg, Russia

Viktor A. Koriachkin

St. Petersburg State Pediatric Medical University, Ministry of Health of Russia, St. Petersburg, Russia

Author for correspondence.
Email: vakoryachkin@mail.ru
ORCID iD: 0000-0002-3400-8989
SPIN-code: 6101-0578

MD, Dr. Sci. (Medicine), Professor

Russian Federation, St. Petersburg, Russia

References

  1. Cheng, D.; Downey, R.J.; Kernstine, K.; Stanbridge, R.; Shennib, H.; Wolf, R.; Ohtsuka, T.; Schmid, R.; Waller, D.; Fernando, H.; et al. Video-Assisted Thoracic Surgery in Lung Cancer Resection: A Meta-Analysis and Systematic Review of Controlled Trials. Innovations 2007, 2, 261–292. doi: 10.1097/IMI.0b013e3181662c6a.
  2. Chen, F.F.; Zhang, D.; Wang, Y.L.; Xiong, B. Video-Assisted Thoracoscopic Surgery LoChen, F.F.; Zhang, D.; Wang, Y.L.; Xiong, B. Video-Assisted Thoracoscopic Surgery Lobectomy versus Open Lobectomy in Patients with Clinical Stage I Non-Small Cell Lung Cancer: A Meta-Analysis. Eur. J. Surg. Oncol. 2013, 39, 957–963bectomy versus Open Lobectomy in Patients with Clinical Stage I Non-Small Cell Lung Cancer: A Meta-Analysis. Eur. J. Surg. Oncol. 2013, 39, 957–963. doi: 10.1093/ejcts/ezv154.
  3. Feray S, Lubach J, Joshi GP, Bonnet F, Van de Velde M; PROSPECT Working Group *of the European Society of Regional Anaesthesia and Pain Therapy. PROSPECT guidelines for video-assisted thoracoscopic surgery: a systematic review and procedure-specific postoperative pain management recommendations. Anaesthesia. 2022 Mar;77(3):311-325. doi: 10.1111/anae.15609.
  4. Scarfe AJ, Schuhmann-Hingel S, Duncan JK, Ma N, Atukorale YN, Cameron AL. Continuous paravertebral block for post-cardiothoracic surgery analgesia: a systematic review and meta-analysis. Eur J Cardiothorac Surg. 2016 Dec;50(6):1010-1018. doi: 10.1093/ejcts/ezw168.
  5. Singh N.P., Makkar J.K., Kuberan A., et al. Efficacy of regional anesthesia techniques for postoperative analgesia in patients undergoing major oncologic breast surgeries: a systematic review and network meta-analysis of randomized controlled trials // Can J Anaesth. 2022. Vol. 69, N. 4. Р. 527–549. doi: 10.1007/s12630-021-02183-z.
  6. Adhikary, S.D.; Pruett, A.; Forero, M.; Thiruvenkatarajan, V. Erector Spinae Plane Block as an Alternative to Epidural Analgesia for Post-Operative Analgesia Following Video-Assisted Thoracoscopic Surgery: A Case Study and a Literature Review on the Spread of Local Anaesthetic in the Erector Spinae Plane. Indian J. Anaesth. 2018, 62, 75–78. doi: 10.4103/ija.IJA_693_17.
  7. Yang, H.-M.; Choi, Y.J.; Kwon, H.-J.; O, J.; Cho, T.H.; Kim, S.H. Comparison of Injectate Spread and Nerve Involvement between Retrolaminar and Erector Spinae Plane Blocks in the Thoracic Region: A Cadaveric Study. Anaesthesia 2018, 73, 1244–1250. doi: 10.1111/anae.14408.
  8. Ivanusic, J.; Konishi, Y.; Barrington, M.J. A Cadaveric Study Investigating the Mechanism of Action of Erector Spinae Blockade. Reg. Anesth. Pain Med. 2018, 43, 567–571. doi: 10.1097/AAP.0000000000000789
  9. Akram M, Iftikhar MR, Fatima Q, Ubaida M, Khan H, Mohsin H, Ibrahim M, Wattoo MAH, Tahir MU, Ali M. Comparative analysis of TPVB and ESPB for postoperative pain management in thoracic and breast surgeries. Future Sci OA. 2024 Dec;10(1):2430852. doi: 10.1080/20565623.2024.2430852.
  10. Oostvogels L, Weibel S, Meißner M, Kranke P, Meyer-Frießem CH, Pogatzki-Zahn E, Schnabel A. Erector spinae plane block for postoperative pain. Cochrane Database Syst Rev. 2024 Feb 12;2(2):CD013763. doi: 10.1002/14651858.CD013763.pub3.
  11. Schnabel A, Weibel S, Pogatzki-Zahn E, Meyer-Frießem CH, Oostvogels L. Erector spinae plane block for postoperative pain. Cochrane Database Syst Rev. 2023 Oct 9;10(10):CD013763. doi: 10.1002/14651858.CD013763.pub2.
  12. Ardon AE, Curley E, Greengrass R. Safety and Complications of Landmark-based Paravertebral Blocks: A Retrospective Analysis of 979 Patients and 4983 Injections. Clin J Pain. 2024 Jun 1;40(6):367-372. doi: 10.1097/AJP.0000000000001208.
  13. Yang, H.-M.; Choi, Y.J.; Kwon, H.-J.; O, J.; Cho, T.H.; Kim, S.H. Comparison of Injectate Spread and Nerve Involvement between Retrolaminar and Erector Spinae Plane Blocks in the Thoracic Region: A Cadaveric Study. Anaesthesia 2018, 73, 1244–1250. doi: 10.1111/anae.14408.
  14. Dautzenberg KHW, Zegers MJ, Bleeker CP, Tan ECTH, Vissers KCP, van Geffen GJ, van der Wal SEI. Unpredictable Injectate Spread of the Erector Spinae Plane Block in Human Cadavers. Anesth Analg. 2019 Nov;129(5):e163-e166. doi: 10.1213/ANE.0000000000004187.
  15. Zhao, H.; Xin, L.; Feng, Y. The Effect of Preoperative Erector Spinae Plane vs. Paravertebral Blocks on Patient-Controlled Oxycodone Consumption after Video-Assisted Thoracic Surgery: A Prospective Randomized, Blinded, Non-Inferiority Study. J. Clin. Anesth. 2020, 62, 109737. doi: 10.1016/j.jclinane.2020.109737.
  16. Taketa, Y.; Irisawa, Y.; Fujitani, T. Comparison of Ultrasound-Guided Erector Spinae Plane Block and Thoracic Paravertebral Block for Postoperative Analgesia after Video-Assisted Thoracic Surgery: A Randomized Controlled Non-Inferiority Clinical Trial. Reg. Anesth. Pain Med. 2019, 45, 10–15. doi: 10.1136/rapm-2019-100827.
  17. Fang, B.; Wang, Z.; Huang, X. Ultrasound-Guided Preoperative Single-Dose Erector Spinae Plane Block Provides Comparable Analgesia to Thoracic Paravertebral Block Following Thoracotomy: A Single Center Randomized Controlled Double-Blind Study. Ann. Transl. Med. 2019, 7, 174. doi: 10.21037/atm.2019.03.53.
  18. Belousova EI, Matinyan NV, Tsintsadze AA, Kovaleva EA. Comparison of regional blocks performed under ultrasound navigation during thoracoscopic surgical interventions in children with malignant neoplasms: prospective randomized single center study. Regional anasthesia and acute pain management. 20224;18(2):155-164. DOI: https://doi.org/10.17816/RA629321
  19. Choi, Y.-J.; Kwon, H.-J.; O, J.; Cho, T.-H.; Won, J.Y.; Yang, H.-M.; Kim, S.H. Influence of Injectate Volume on Paravertebral Spread in Erector Spinae Plane Block: An Endoscopic and Anatomical Evaluation. PLoS ONE 2019, 14, e0224487. doi: 10.1371/journal.pone.0224487.
  20. Zhang L, Hu Y, Liu H, Qi X, Chen H, Cao W, Wang L, Zhang Y, Wu Y. Analgesic Efficacy of Combined Thoracic Paravertebral Block and Erector Spinae Plane Block for Video-Assisted Thoracic Surgery: A Prospective Randomized Clinical Trial. Med Sci Monit. 2023 Jul 6;29:e940247. doi: 10.12659/MSM.940247.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) Eco-Vector



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ ФС 77 - 55827 от 30.10.2013 г
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ЭЛ № ФС 77 - 80651 от 15.03.2021 г
.