Application of bispectral index and analgesia nociception index monitoring during laparoscopic cholecystectomy

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The study provides a theoretical generalization and substantive solution to the scientific and practical problem of increasing the efficiency of anesthesia for surgical interventions, such as laparoscopic cholecystectomy, under individualized anesthetic support. This study also presents the peculiar courses of various anesthetic methods during the perioperative period in 120 patients with cholelithiasis who underwent laparoscopic cholecystectomy. Anesthesia types included total intravenous anesthesia using propofol and inhalation anesthesia with sevoflurane. Monitoring the bispectral index and analgesia and nociception index has been widely performed to assess the adequacy of various anesthetic options. These indices were also monitored to assess hemodynamic and autonomic regulation parameters in real time and to predict changes in these parameters intraoperatively. The results suggested the broad possibilities of monitoring, controlling, and minimizing the effect anesthesia on the cardiovascular system in conditions associated with a transient increase in the intra-abdominal pressure.

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About the authors

A. M. Mashyn

«Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine»

Ukraine, 49044, Dnipro

Yuriy Y. Kobelyatskiy

«Dnipropetrovsk Medical Academy of the Ministry of Health of Ukraine»

Author for correspondence.

Doctor of Medical Sciences, Professor, Head of the Department of Anesthesiology and Intensive Care, State Institution “Dnepropetrovsk Medical Academy of the Ministry of Health of Ukraine”

Ukraine, 49044, Dnipro


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Supplementary files

Supplementary Files
1. Fig. 1. Comparison of the dynamics of mean values MAP (M, 95% CI) in the study groups

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2. Fig. 2. Comparison of the dynamics of the average BIS indicators (M, 95% CI) in the study groups

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3. Fig. 3. Comparison of the dynamics of average ANI indicators (M, 95% CI) in the study groups

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4. Fig. 4. Comparison of the mean values of time characteristics (Me (25–75%)) in the study groups

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