Vol 7, No 4 (2013)

The study was performed to compare thoracic epidural anaesthesia and esmolol infusion capability to provide optimal hemodynamic conditions for myocardial functioning. The study included 45 patients with increased cardiac risk undergoing opened abdominal surgery. The patients were randomized to receive either intravenous anaesthesia or combined (intravenous + thoracic epidural) anaesthesia or intravenous anaesthesia with esmolol infusion. The study results demonstrate that thoracic epidural anaesthesia and esmolol infusion provide effective control of hemodynamic response to trachea intubation and prevent tachycardia during the procedure. B-type natriuretic peptide level decreased during surgery while using two pointed techniques in contrast to the intravenous anaesthesia alone. This fact indicates comfortable conditions for myocardial functioning and proves that these techniques are cardioprotective.

Objective: optimization of regional anesthesia for major spine surgery and the evaluation of its effects on the endocrine-metabolic and inflammatory stress response. This study included 205 patients. Two groups of patients were randomly allocated: Group 1 used thoracic epidural analgesia and general anesthesia, and Group 2 had general anesthesia. The study has shown that epidural analgesia provided better pain relief, less blood loss during and after surgery in spinal deformity surgery. The use of epidural analgesia provided better pain control, less bleeding, and a lower surgical stress response than general anesthesia during major spine surgery.

This prospective, randomized, multicenter trial evaluated the risks of death, increased surgical site bleeding, gastrointestinal bleeding, acute renal failure, and allergic reactions, with ketorolac vs diclofenac or ketoprofen administered according to their approved parenteral and oral dose duration of treatment. Patients were followed for 30 days after surgery. It was concluded that ketorolac is as safe as ketoprofen and diclofenac for the treatment of pain major surgery.

The authors present detailed observation of successful treating of patient with severe polytrauma where thoracic epidural analgesia was performed not only for postoperative pain management but also for optimization of programmed continuous mechanical ventilation