Comparison of hemodynamic parameters in patients during transcuretral resection of the urinary bubble during spinal anesthesia using levobupivakaina and popivacaine

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Abstract

Summary. The aim of the study was to compare hemodynamic changes when using ropivacaine and levobupivacaine in patients during spinal anesthesia. Materials and methods: The study included 48 patients who were randomized into two groups, depending on the anesthetic used: group P – ropivacaine, group L – levobupivacaine. Changes in mean arterial pressure and heart rate were evaluated. Results: patients in group L showed stable hemodynamic parameters. On the contrary, in the group P for 12 min, arterial hypotension was registered in 45.8% of the subjects, for 15 min it was detected in 37.5% of cases. At 18 min, a decrease in mean arterial pressure was observed in 41.6% of patients, while in 12.5% of cases it was necessary to connect vasopressor support for norepinephrine in a dosage of 0.07–0.15 μg/kg/min. When analyzing the heart rate of less than 60 beats/min in group L was not identified. At the same time, in group P, sinus bradycardia was registered at all stages of control of the heart rate, and in some cases atropine correction was required. Conclusions: the course of anesthesia in the group using levobupivacaine was characterized by stable mean arterial pressure and heart rate. Patients in the ropivacaine group showed a decrease in mean arterial pressure of less than 70 mm Hg. in a controlled period of time from 12.5% to 48.5% for the purpose of correction of which, use of vasopressor support was required by 12.5%. Bradycardia in this group was registered in 12.5% -54.1% of cases, while atropine was used in 12.5%.

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About the authors

Kirill A. Tsygankov

Military Medical Academy named after S. M. Kirov of the Ministry of Defense of Russian Federation

Author for correspondence.
Email: doctorcygankov@mail.ru
ORCID iD: 0000-0002-2357-0685

MD, PhD, lecturer of the department of anesthesiology and reanimatology

Russian Federation, St. Petersburg

A. H. Korepanov

St. Petersburg State Healthcare Institution «City Clinical Oncology Center»

Email: doctorcygankov@mail.ru
ORCID iD: 0000-0002-6472-2868
Russian Federation, St. Petersburg

R. E. Lakhin

Military Medical Academy named after S. M. Kirov of the Ministry of Defense of Russian Federation

Email: doctorcygankov@mail.ru
ORCID iD: 0000-0001-6819-9691
Russian Federation, St. Petersburg

A. V. Shchegolev

Military Medical Academy named after S. M. Kirov of the Ministry of Defense of Russian Federation

Email: doctorcygankov@mail.ru
ORCID iD: 0000-0001-6431-439X
Russian Federation, St. Petersburg

A. D. Khalikov

St. Petersburg State Healthcare Institution «City Clinical Oncology Center»

Email: doctorcygankov@mail.ru
ORCID iD: 0000-0001-9864-1284
Russian Federation, St. Petersburg

A. I. Matich

Military Medical Academy named after S. M. Kirov of the Ministry of Defense of Russian Federation

Email: doctorcygankov@mail.ru
ORCID iD: 0000-0003-4387-0041
Russian Federation, St. Petersburg

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Supplementary files

Supplementary Files
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1. Figure: 1. Changes in SBP in the ropivacaine and levobupivacaine groups

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2. Figure: 2. Change in heart rate in the ropivacaine and levobupivacaine groups

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