Synthesis and conversions of benzo-substituted 1-[2-methyl4-(methyltio)quinolin-3-yl]propan-2-ones

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Abstract

New derivatives of Schiff bases were synthesized using 1-[2-methyl-4-mercaptoquinolin-3-yl]propan-2-ones and 1-[2-methyl-4-(methylthio)quinoline substituted in the benzene ring-3- yl]propan-2-ones as starting materials. To obtain the 4-methylthio derivatives of the Schiff base, the corresponding 4-mercaptoquinoline-propan-2-ones and 3-(2-chloroallyl)-4-mercaptoquinolines were first methylated, followed by acid hydrolysis of the chloro allyl group in the latter samples.

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I. L. Aleksanyan

Yerevan State University

Author for correspondence.
Email: ialeksanyan@ysu.am
ORCID iD: 0000-0002-4039-2323
Armenia, ul. Aleka Manukyana, 1, Yerevan, 375025

L. P. Hambardzumyan

Yerevan State University

Email: ialeksanyan@ysu.am
ORCID iD: 0000-0003-1210-0052
Armenia, ul. Aleka Manukyana, 1, Yerevan, 375025

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