Physiological and hygienic validation of the health benefits of garlic salt to prevent arterial hypertension
- Authors: Tsikunib A.D.1, Ezlyu F.N.1, Shartan R.R.2, Alimkhanova A.A.3
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Affiliations:
- Adyghe State University of the Ministry of Science and Higher Education of the Russian Federation
- City Policlinic No. 7 in Krasnodar
- Akhmat Abdulhamidovich Kadyrov Chechen State University
- Issue: Vol 101, No 4 (2022)
- Pages: 425-432
- Section: FOOD HYGIENE
- Published: 06.05.2022
- URL: https://rjraap.com/0016-9900/article/view/639351
- DOI: https://doi.org/10.47470/0016-9900-2022-101-4-425-432
- ID: 639351
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Full Text
Abstract
Introduction. From hygienic point of view, the consumption of table salt (TS) neither below nor above the physiological norm is relevant to ensure normal biochemical processes of sodium metabolism in the body.
The aim of the study was a physiological and hygienic validation of the health benefits of Adyghe garlic salt (GS), made by using traditional technology, for optimizing the level of NaCl consumption and prevention arterial hypertension.
Materials and methods. Seventy-one adolescent girl aged 12–15 years and 124 women aged 38.5±4.2 years of Adyg nationality took part in the studies. The attitude to GS and the level of its consumption were revealed by the method of focus groups, questionnaires and analysis of 3-day diets. Blood pressure indicators were determined by the oscillometric method, the content of albumin in morning urine — by the ICA method, the taste sensitivity threshold to salt (STST) — by the density measurement method, the efficiency of achieving a salty taste when using GS — by the tasting analysis method.
Results. Adolescent girls and women from families regularly using garlic salt (GS) in home cooking have been found to have low levels of NaCl consumption (LLNaClC). In families that do not use GS in practice, a high level of NaCl consumption (HLCNaCl) is detected. The STST values are reliably lower in LLNaClC groups. GS compared to TS is more effective in achieving salty taste by 23.2±1.84%. In the group of women with LLNaClC, blood pressure indices are lower, microalbuminuria is not detected.
Limitations. To substantiate the effectiveness of the use of GS to optimize the level of NaCl consumption and to carry out prevention of arterial hypertension, we took only female persons of the Adyghe nationality as participants of research. In the future, it is planned to expand research taking into account gender and national aspects.
Conclusion. GS reduces the NaCl consumption without disturbing hedonistic perception of taste. Increasing public awareness of the benefits of GS in achieving salty taste and its widespread introduction into the modern nutritional system of various populations can be an effective hygienic approach to optimizing NaCl consumption, and reducing the risk of arterial hypertension.
Contribution:
Tsikunib A.D. — research concept and design, material collection, research and data processing, writing;
Ezlyu F.N. — collecting material, conducting research and processing data, and writing and editing the text;
Shartan R.R. — collecting data from the literature, gathering material, conducting research, and processing data;
Alimkhanova A.A. — literature data collection, data processing.
All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.
Conflict of interest. The authors declare no conflict of interest.
Acknowledgement. The study had no sponsorship.
Received: January 19, 2022 / Accepted: April 12, 2022 / Published: April 30, 2022
About the authors
Aminet D. Tsikunib
Adyghe State University of the Ministry of Science and Higher Education of the Russian Federation
Author for correspondence.
Email: cikunib58@mail.ru
ORCID iD: 0000-0002-7491-0539
MD, PhD, DSci., Professor, Head of the Laboratory of Nutrition and Ecology, Research Institute of Complex Problems of Adyghe State University, Maykop, 385000, Russian Federation.
e-mail: cikunib58@mail.ru
Russian FederationFatima N. Ezlyu
Adyghe State University of the Ministry of Science and Higher Education of the Russian Federation
Email: noemail@neicon.ru
ORCID iD: 0000-0002-6693-6632
Russian Federation
Ruzanna R. Shartan
City Policlinic No. 7 in Krasnodar
Email: noemail@neicon.ru
ORCID iD: 0000-0002-6900-2333
Russian Federation
Aminat A. Alimkhanova
Akhmat Abdulhamidovich Kadyrov Chechen State University
Email: noemail@neicon.ru
ORCID iD: 0000-0002-2706-4499
Russian Federation
References
- Xu N. On the concept of resting potential–pumping ratio of the Na+/K+ pump and concentration ratios of potassium ions outside and inside the cell to sodium ions inside and outside the cell. J. Membr. Biol. 2013; 246(1): 75–90. https://doi.org/10.1007/s00232-012-9507-6
- DiNicolantonio J.J., Lucan S.C. The wrong white crystals: not salt but sugar as aetiological in hypertension and cardiometabolic disease. Open Heart. 2014; 1(1): e000167. https://doi.org/10.1136/openhrt-2014-000167
- Braam B., Huang X., Cupples W.A., Hamza S.M. Understanding the two faces of low-salt intake. Curr. Hypertens. Rep. 2017; 19(6): 49. https://doi.org/10.1007/s11906-017-0744-z
- Gorbatkova E.Yu. Study of actual nutrition in modern student youth. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2020; 99(3): 291–7. https://doi.org/10.33029/0016-9900-2020-99-3-291-297 (in Russian)
- Bhat S., Marklund M., Henry M.E., Appel L.J., Croft K.D., Neal B., et al. Systematic Review of the sources of dietary salt around the world. Adv. Nutr. 2020; 11(3): 677–86. https://doi.org/10.1093/advances/nmz134
- Poteshkina N.G. Salt intake, arterial hypertension, and cardiovascular risk. Part II. Rossiyskiy kardiologicheskiy zhurnal. 2011; (5): 93–102. (in Russian)
- Abramovich S.G. Taste sensitivity to table salt in healthy subjects and hypertensive patients. Byulleten’ Vostochno-Sibirskogo nauchnogo tsentra sibirskogo otdeleniya rossiyskoy akademii meditsinskikh nauk. 2004; (1–3): 12–6. (in Russian)
- Balanova Yu.A., Kontsevaya A.V., Karamnova N.S., Mukaneeva D.K., Drapkina O.M. Population-based cardiovascular disease prevention measures aimed at reducing salt intake: analysis of international strategies and prospects for implementation in the Russian Federation. Ratsional’naya farmakoterapiya v kardiologii. 2020; 16(6): 966–76. https://doi.org/10.20996/1819-6446-2020-12-08 (in Russian)
- Stamler J., Elliott P., Dennis B., Dyer A.R., Kesteloot H., Liu K., et al. INTERMAP: background, aims, design, methods, and descriptive statistics (nondietary). J. Hum. Hypertens. 2003; 17(9): 591–608. https://doi.org/10.1038/sj.jhh.1001603
- The Multiple Risk Factor Intervention Trial Research Group. Mortality after 16 years for participants randomized to the multiple risk factor intervention trial. Circulation. 1996; 94: 946–51. https://doi.org/10.1161/01.cir.94.5.946
- Intersalt Cooperative Research Group. Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. BMJ. 1988; 297(6644): 319–28. https://doi.org/10.1136/bmj.297.6644.319
- Diet, Nutrition, and the Prevention of Chronic Diseases. World Health Organ. Tech. Rep. Ser. 2003; 916: i–viii, 1–149, backcover.
- Lloyd-Jones D.M., Hong Y., Labarthe D., Mozaffarian D., Appel L.J., Van Horn L., et al. Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association’s strategic Impact Goal through 2020 and beyond. Circulation. 2010; 121(4): 586–613. https://doi.org/10.1161/Circulationaha.109.192703
- MR 2.3.1.0253-21. Norms of physiological requirements for energy and nutrients for various groups of the population of the Russian Federation. Moscow; 2021. (in Russian)
- Appel L.J., Frohlich E.D., Hall J.E., Pearson T.A., Sacco R.L., Seals D.R., et al. AHA Presidential Advisory. The Importance of population-wide sodium reduction as a means to prevent cardiovascular disease and stroke. A call to action from the American heart association. Circulation. 2011; 123(10): 1138–43. https://doi.org/10.1161/cir.0b013e31820d0793
- WHO. Action plan for the prevention and control of noncommunicable diseases in the WHO European Region 2016–2025. Available at: https://www.euro.who.int/en/health-topics/noncommunicable-diseases/obesity/publications/2016/action-plan-for-the-prevention-and-control-of-noncommunicable-diseases-in-the-who-european-region-20162025
- Aviv A. Salt and hypertension: the debate that begs the bigger question. Arch. Intern. Med. 2001; 161(4): 507–10. https://doi.org/10.1001/archinte.161.4.507
- Heaney R.P. Making sense of the science of sodium. Nutrition. Today. 2015; 50(2): 63–6. https://doi.org/10.1097/nt.0000000000000084
- Johnson C., Praveen D., Pope A., Raj T.S., Pillai R.N., Land M.A., et al. Mean population salt consumption in India: a systematic review. J. Hyperten. 2017; 35(1): 3–9. https://doi.org/10.1097/hjh.0000000000001141
- Konstantinov E.N., Nekrasova A.A., Gundarov I.A., Dergacheva O.V., Musaev Z.M. Determination of the thresholds of taste sensitivity to table salt in a population study. Byulleten’ vsesoyuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR. 1983; 6(1): 30–5. (in Russian)
- Scaglioni S., Arrizza C., Vecchi F., Tedeschi S. Determinants of children’s eating behavior. Am. J. Clin. Nutr. 2011; 94(6 Suppl.): 2006S–11S. https://doi.org/10.3945/ajcn.110.001685
- Shebanova V.I., Shebanova S.G. Family influence on the formation of eating disorders in children and adolescents. In: V International Congress «Young Generation XXI century: Actual problems of social and psychological health» [V Mezhdunarodnyy kongress “Molodoe pokolenie XXI veka: Aktual’nye problemy sotsial’no-psikhologicheskogo zdorov’ya”]. Moscow; 2013; 327–8. (in Russian)
- Liedtke W.B., McKinley M.J., Walker L.L., Zhang H., Pfenning A.R., Drago J., et al. Relation of addiction genes to hypothalamic gene changes subserving genesis and gratification of a classic instinct, sodium appetite. Proc. Natl. Acad. Sci. USA. 2011; 108(30): 12509–14. https://doi.org/10.1073/pnas.1109199108
- Ried K. Garlic lowers blood pressure in hypertensive individuals, regulates serum cholesterol, and stimulates immunity: an updated meta-analysis and review. J. Nutr. 2016; 146(2): 389S–96S. https://doi.org/10.3945/jn.114.202192
- Munakata M., Konno S., Ohshima M., Ikeda T., Miura Y., Ito S. High-normal blood pressure is associated with microalbuminuria in the general population: the Watari study. Hypertens. Res. 2011; 34(10): 1135–40. https://doi.org/10.1038/hr.2011.98
- Konno S., Hozawa A., Miura Y., Ito S., Munakata M. High-normal diastolic blood pressure is a risk for development of microalbuminuria in the general population: the Watari study. J. Hypertens. 2013; 31(4): 798–804. https://doi.org/10.1097/hjh.0b013e32835e2146
- He F.J., MacGregor G.A. How far should salt intake be reduced? Hypertension. 2003; 42(6): 1093–9. https://doi.org/10.1161/01.hyp.0000102864.05174.e8
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