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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Regional Anesthesia and Acute Pain Management</journal-id><journal-title-group><journal-title xml:lang="en">Regional Anesthesia and Acute Pain Management</journal-title><trans-title-group xml:lang="ru"><trans-title>Регионарная анестезия и лечение острой боли</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1993-6508</issn><issn publication-format="electronic">2687-1394</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">678568</article-id><article-id pub-id-type="doi">10.17816/RA678568</article-id><article-id pub-id-type="edn">SOAJZK</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">A Case Report of Erector Spinae Plane Block Application During Abdominal Surgery in an Infant With Coagulation Disorder</article-title><trans-title-group xml:lang="ru"><trans-title>Клинический случай применения ESP-блока при хирургическом вмешательстве у ребёнка грудного возраста с нарушением коагуляции</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4394-818X</contrib-id><contrib-id contrib-id-type="spin">2306-6930</contrib-id><name-alternatives><name xml:lang="en"><surname>Murashova</surname><given-names>Olga A.</given-names></name><name xml:lang="ru"><surname>Мурашова</surname><given-names>Ольга Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>murashowa.olya2013@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-7357-2223</contrib-id><contrib-id contrib-id-type="spin">1101-2442</contrib-id><name-alternatives><name xml:lang="en"><surname>Zelenin</surname><given-names>Nazar M.</given-names></name><name xml:lang="ru"><surname>Зеленин</surname><given-names>Назар Мартович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>piorun1944@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7491-4153</contrib-id><contrib-id contrib-id-type="spin">7333-9506</contrib-id><name-alternatives><name xml:lang="en"><surname>Ulrikh</surname><given-names>Gleb E.</given-names></name><name xml:lang="ru"><surname>Ульрих</surname><given-names>Глеб Эдуардович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>ostrovgl@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1008-3626</contrib-id><contrib-id contrib-id-type="spin">4205-6067</contrib-id><name-alternatives><name xml:lang="en"><surname>Dvoretskiy</surname><given-names>Vladislav S.</given-names></name><name xml:lang="ru"><surname>Дворецкий</surname><given-names>Владислав Сергеевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD</p></bio><email>butler4@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Saint Petersburg State Pediatric Medical University</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский государственный педиатрический медицинский университет</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2025-10-09" publication-format="electronic"><day>09</day><month>10</month><year>2025</year></pub-date><pub-date date-type="pub" iso-8601-date="2025-11-06" publication-format="electronic"><day>06</day><month>11</month><year>2025</year></pub-date><volume>19</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>262</fpage><lpage>269</lpage><history><date date-type="received" iso-8601-date="2025-04-16"><day>16</day><month>04</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-09-15"><day>15</day><month>09</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2025, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2025, Эко-Вектор</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://eco-vector.com/for_authors.php#07</ali:license_ref></license></permissions><self-uri xlink:href="https://rjraap.com/1993-6508/article/view/678568">https://rjraap.com/1993-6508/article/view/678568</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND:</bold> This article presents a clinical case of combined anesthesia during abdominal surgery in which the analgesic component was provided by a bilateral erector spinae plane (ESP) block using 0.2% ropivacaine in a 2-month-old infant with a coagulation disorder. Selecting an optimal method of analgesia in pediatric patients requiring surgical intervention remains one of the most challenging issues in medicine. The use of regional analgesia as part of multimodal anesthesia is a safe and effective approach to perioperative pain management in neonates and infants. Epidural anesthesia is widely used and classified as a neuraxial block; however, despite its advantages, it has some contraindications and may be associated with rare but significant complications. Therefore, peripheral nerve blocks are increasingly used as an alternative.</p> <p><bold>CASE DESCRIPTION:</bold> This article demonstrates the feasibility and effectiveness of the ESP block as an alternative to epidural anesthesia in an infant admitted from a regional hospital at the age of 2 months and 3 days, presenting with hepatic failure and impaired hemostasis confirmed by laboratory blood tests. Immediately after birth, the patient required respiratory support for 29 days. The infant was admitted for further evaluation, diagnostic clarification, and treatment. After a series of additional examinations, a decision was made to perform surgery, including liver biopsy and cholecystocholangiography. Coagulation abnormalities in the blood test contraindicated epidural anesthesia. Consequently, to reduce the risks of ventilatory support and facilitate early enteral nutrition in the postoperative period, an ESP block was chosen as the method of regional anesthesia. The ESP block is a peripheral nerve block performed under ultrasound guidance, for which hemostatic disorders are not an absolute contraindication. Thus, effective multimodal postoperative analgesia was achieved without opioids; mechanical ventilation was not required, and early enteral feeding was successfully initiated.</p> <p><bold>CONCLUSION: </bold>This clinical case demonstrates the feasibility of using the ESP block as an alternative to epidural anesthesia as part of combined anesthesia in infants undergoing abdominal surgery. The use of peripheral nerve blocks is not limited by hypocoagulation. Given its technical simplicity and the use of ultrasound guidance, the risk of bleeding associated with the ESP block is minimal. This method may serve as a reliable component of multimodal anesthesia in children, including those in the neonatal period.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Актуальность.</bold> В статье представлен клинический случай проведения сочетанной анестезии при операции на органах брюшной полости с анальгетическим компонентом, обеспеченным ESP-блоком 0,2% раствором ропивакаина с двух сторон у ребёнка двух месяцев жизни с нарушением коагуляции. Выбор оптимального способа обезболивания у детей, нуждающихся в оперативном вмешательстве, является одной из самых актуальных проблем медицины. Применение регионарной аналгезии в контексте мультимодальной анестезии — безопасный и эффективный метод периоперационного обезболивания у новорождённых и детей грудного возраста. Достаточно часто используется эпидуральная анестезия, которая относится к нейроаксиальным блокам и, несмотря на свои преимущества, имеет ряд противопоказаний, а также может сопровождаться редкими, но значимыми осложнениями. В связи с этим последнее время всё чаще прибегают к использованию периферических блоков.</p> <p><bold>Описание клинического случая.</bold> В статье демонстрируется возможность эффективного применения ESP-блока как альтернативы эпидуральной анестезии у ребёнка, прибывшего в стационар из региона в возрасте 2 месяцев и 3 суток жизни с имеющейся печёночной недостаточностью и нарушением гемостаза, что подтверждено в лабораторных исследованиях крови. Сразу после рождения пациентка нуждалась в респираторной поддержке в течение 29 суток жизни. В стационар ребёнок поступил с целью дообследования, уточнения диагноза и дальнейшего лечения. После проведения ряда дополнительных исследований было принято решение о необходимости проведения оперативного вмешательства в объёме биопсии печени и холецистохолангиографии. Наличие нарушения гемостаза в показателях крови явилось противопоказанием для применения эпидуральной анестезии, в связи с этим, с целью снижения рисков вентиляционной поддержки и реализации энтерального питания в раннем послеоперационном периоде, в качестве регионарной анестезии решили использовать ESP-блок, который относится к периферическим блокам, проводится с использованием ультразвуковой навигации и не имеет в абсолютных противопоказаниях нарушение гемостаза. Таким образом, в послеоперационном периоде было достигнуто качественное мультимодальное обезболивание без использования опиоидов, не потребовалась искусственная вентиляция лёгких, и было реализовано раннее начало энтерального питания.</p> <p><bold>Заключение.</bold> Представленный клинический случай демонстрирует возможность применения ESP-блока в качестве альтернативы эпидуральной анестезии в составе сочетанной анестезии у детей первых месяцев жизни во время хирургического вмешательства на органах брюшной полости. Применение периферических блокад не ограничено наличием гипокоагуляции. Риск возникновения кровотечения при ESP-блоке минимален, учитывая техническую простоту и ультразвуковую навигацию. Этот метод может стать надёжным компонентом мультимодальной анестезии у детей, начиная с периода новорождённости.</p></trans-abstract><kwd-group xml:lang="en"><kwd>infants</kwd><kwd>combined anesthesia</kwd><kwd>regional anesthesia</kwd><kwd>ESP block</kwd><kwd>multimodal analgesia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>грудные дети</kwd><kwd>комбинированная анестезия</kwd><kwd>регионарная анестезия</kwd><kwd>ESP-блок</kwd><kwd>мультимодальная аналгезия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Zhirkova YV, Kucherov YI, Stepanenko SM. Pain in neonates: prevalence, diagnostics, prevention and treatment. Pediatric pharmacology. 2012;9(4):37–41. EDN: PBXYJH</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Matinian NV, Saltanov AI. General anesthesia in combination with neuraxial blockade in pediatric oncologic surgery. 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