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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Regional Anesthesia and Acute Pain Management</journal-id><journal-title-group><journal-title xml:lang="en">Regional Anesthesia and Acute Pain Management</journal-title><trans-title-group xml:lang="ru"><trans-title>Регионарная анестезия и лечение острой боли</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1993-6508</issn><issn publication-format="electronic">2687-1394</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">62416</article-id><article-id pub-id-type="doi">10.17816/RA62416</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Epidural blockade in thoracic surgery: a case report</article-title><trans-title-group xml:lang="ru"><trans-title>Эпидуральная блокада в торакальной хирургии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5147-5637</contrib-id><name-alternatives><name xml:lang="en"><surname>Zhikharev</surname><given-names>Vasiliy A.</given-names></name><name xml:lang="ru"><surname>Жихарев</surname><given-names>Василий Александрович</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Researcher of the Department of Anesthesiology and Reanimation, State Public Health Budget Institution ‘Scientific Research Institute – Ochapovsky Regional Clinic Hospital №1</p></bio><bio xml:lang="ru"><p>к.м.н., научный сотрудник отдела анестезиологии и реанимации ГБУЗ «НИИ – ККБ № 1 им. проф. С.В. Очаповского» Министерства здравоохранения Краснодарского края</p></bio><email>Vasilii290873@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1427-4032</contrib-id><name-alternatives><name xml:lang="en"><surname>Bushuev</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Бушуев</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>Vasilii290873@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5851-1781</contrib-id><name-alternatives><name xml:lang="en"><surname>Larin</surname><given-names>V. F.</given-names></name><name xml:lang="ru"><surname>Ларин</surname><given-names>В. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>Vasilii290873@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3400-8989</contrib-id><name-alternatives><name xml:lang="en"><surname>Koryachkin</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Корячкин</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>Vasilii290873@yandex.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">State-Financed Institution of Public Health “Scientific Research Institution – Ochapovsky Regional Clinic Hospital # 1” Krasnodar Region Public Health Ministry</institution></aff><aff><institution xml:lang="ru">ГБУЗ «НИИ – ККБ №1 им. проф. С.В. Очаповского» Министерства здравоохранения Краснодарского края</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">State Public Educational Budget Institution Russian Ministry of Health SPbPMU Public Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «СПбГПМУ» Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-12-08" publication-format="electronic"><day>08</day><month>12</month><year>2020</year></pub-date><volume>14</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>224</fpage><lpage>227</lpage><history><date date-type="received" iso-8601-date="2021-03-01"><day>01</day><month>03</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-03-01"><day>01</day><month>03</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2020, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2020, ООО "Эко-Вектор"</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2023-12-08"/></permissions><self-uri xlink:href="https://rjraap.com/1993-6508/article/view/62416">https://rjraap.com/1993-6508/article/view/62416</self-uri><abstract xml:lang="en"><p>This report presents a clinical case of the treatment of pain syndrome in isolated chest trauma following an accident of a patient with liver cirrhosis and hypocoagulation syndrome who sustained bilateral fracture of the ribs (II, III, IV, V, and VI ribs on the right and II, III, IV, V, and VI ribs on the left), fracture of the sternum body in the middle third, bilateral hemopneumothorax, and contusion of both lungs. From the initial hours, fentanyl, which was administered intravenously in a complex of multimodal analgesia, was used for anesthesia. However, adequate pain control was not achieved. Against the background of pain syndrome, the patient developed impaired consciousness and respiratory failure. Epidural puncture and catheterization with an epidural injection of ropivacaine were performed, which relieved the pain syndrome and helped prevent pulmonary complications. The present case highlights the need for an individual assessment of the risk–benefit ratio of the use of epidural catheterization in patients with coagulopathy.</p> <p>Conclusion: The use of epidural analgesia for chest trauma in patients with moderate coagulopathy made it possible to initiate effective analgesia and reduce the risk of respiratory complications, which ultimately ensured a favorable outcome of severe trauma.</p></abstract><trans-abstract xml:lang="ru"><p>Представлен клинический случай лечения болевого синдрома при изолированной травме грудной клетки в результате ДТП: двусторонний перелом рёбер (II, III, IV, V, VI рëбер справа и II, III, IV, V, VI рëбер слева), перелом тела грудины в средней трети, двусторонний гемопневмоторакс, ушиб обоих лёгких у пациента с циррозом печени и синдромом гипокоагуляции. С первых часов для обезболивания использовалось внутривенное введение фентанила в комплексе мультимодальной анальгезии, однако адекватного контроля болевого синдрома достигнуть не удалось. При этом на фоне болевого синдрома развились нарушение сознания и дыхательная недостаточность. Проведена эпидуральная пункция и катетеризация с эпидуральным введением ропивакаина, что купировало болевой синдром и способствовало профилактике лёгочных осложнений. В статье демонстрируется необходимость индивидуальной оценки соотношения риска и пользы применения катетеризации эпидурального пространства у пациентов с коагулопатией. Вывод: применение эпидуральной анальгезии при травме грудной клетки в условиях умеренной коагулопатии позволило провести эффективную анальгезию, снизить риск развития респираторных осложнений, что в конечном итоге обеспечило благоприятный исход тяжëлой травмы.</p></trans-abstract><kwd-group xml:lang="en"><kwd>epidural analgesia</kwd><kwd>rib fractures</kwd><kwd>chest trauma</kwd><kwd>hypocoagulation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эпидуральная анальгезия</kwd><kwd>переломы рёбер</kwd><kwd>травма грудной клетки</kwd><kwd>гипокоагуляция</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Haines K.L., Zens T., Warner-Hillard C., DeSouza E., Jung H.S., Agarwal S. Rib Fracture Location Should Be Evaluated When Predicting Morbidity and Mortality in Trauma Patients // Am Surg. 2018. Vol. 84. N 9. Р. 1462–5. PMID: 30268176.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Flagel B.T., Luchette F.A., Reed R.L., Esposito T.J., Davis K.A., Santaniello J.M., Gamelli R.L. Half-a-dozen ribs: the breakpoint for mortality // Surgery. 2005 Oct; Vol. 138. N 4. P. 717–23; discussion 723-5. DOI: 10.1016/j.surg.2005.07.022.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Fabricant L., Ham B., Mullins R., Mayberry J. Prolonged pain and disability are common after rib fractures // Am J Surg. 2013. Vol. 205. N 5. Р. 511–5. DOI 10.1016/j.amjsurg.2012. 12.007.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Chen J., Jeremitsky E., Philp F., Fry W., Smith R.S. A chest trauma scoring system to predict outcomes // Surgery. 2014 Oct. Vol. 156. N 4. P. 988–93. DOI 10.1016/j.surg.2014.06.045.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Battle C., Hutchings H., Lovett S., Bouamra O., Jones S., Sen A., et al. Predicting outcomes after blunt chest wall trauma: development and external validation of a new prognostic model // Crit Care. 2014 May 14. Vol. 18. N 3. P. R98. DOI: 10.1186/cc13873.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Zaw A.A., Murry J., Hoang D., Chen K., Louy C., Bloom M.B., et al. Epidural Analgesia after Rib Fractures // Am Surg. 2015 Oct. Vol. 81. N 10. P. 950–4. PMID: 26463287.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Bachoumas K., Levrat A., Le Thuaut A., Rouleau S., Groyer S., Dupont H., et al. Epidural analgesia in ICU chest trauma patients with fractured ribs: retrospective study of pain control and intubation requirements // Ann Intensive Care. 2020 Aug 27. Vol. 10. N 1. P. 116. DOI: 10.1186/s13613-020-00733-0.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Mai H.T., Tran T.S., Ho-Le T.P., Pham T.T., Center J.R., Eisman J.A., et al. Low-trauma rib fracture in the elderly: Risk factors and mortality consequence // Bone. 2018. Vol. 116. Р. 295–300. DOI: 10.1016/j.bone.2018.08.016.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>McKendy K.M., Lee L.F., Boulva K., Deckelbaum D.L., Mulder D.S., Razek T.S., et al. Epidural analgesia for traumatic rib fractures is associated with worse outcomes: a matched analysis // J Surg Res. 2017 Jun. Vol. 15. N 214 P. 117–23. DOI: 10.1016/j.jss.2017.02.057.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>IsHak W.W., Wen R.Y., Naghdechi L., Vanle B., Dang J., Knosp M., et al. Pain and Depression: A Systematic Review // Harv Rev Psychiatry. 2018. Vol. 26. N 6. Р. 352–63. DOI: 10.1097/HRP.0000000000000198.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Bolliger C.T., Van Eeden S.F. Treatment of multiple rib fractures. Randomized controlled trial comparing ventilatory with nonventilatory management // Chest. 1990 Apr. Vol. 97. N 4. P. 943–8. DOI: 10.1378/chest.97.4.943. PMID: 2182301.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Horst K., Andruszkow H., Weber C.D., Pishnamaz M., Herren C., Zhi Q., et al. Thoracic trauma now and then: A 10 year experience from 16,773 severely injured patients // PLoS One. 2017 Oct. Vol. 19. N 12. P. 10:e0186712. DOI: 10.1371/journal.pone.0186712.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Galvagno S.M. Jr., Smith C.E., Varon A.J., Hasenboehler E.A., Sultan S., Shaefer G., et al. Pain management for blunt thoracic trauma: A joint practice management guideline from the Eastern Association for the Surgery of Trauma and Trauma Anesthesiology Society // J Trauma Acute Care Surg. 2016 Nov. Vol. 81. N 5. P. 936–51. DOI: 10.1097/TA.0000000000001209.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Gage A., Rivara F., Wang J., Jurkovich G.J., Arbabi S. The effect of epidural placement in patients after blunt thoracic trauma // J Trauma Acute Care Surg. 2014 Jan. 76. N 1. P. 39–45; discussion 45–6. DOI: 10.1097/TA.0b013e3182ab1b08.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Malekpour M., Hashmi A., Dove J., Torres D., Wild J. Analgesic Choice in Management of Rib Fractures: Paravertebral Block or Epidural Analgesia? // Anesth Analg. 2017 Jun. Vol. 124. N 6. P. 1906–11. DOI: 10.1213/ANE.0000000000002113.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Gulur P., Tsui B., Pathak R., Koury K.M., Lee H. Retrospective analysis of the incidence of epidural haematoma in patients with epidural catheters and abnormal coagulation parameters // Br J Anaesth. 2015. Vol. 114. N 5. Р. 808–11. DOI: 10.1093/bja/aeu461.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Estcourt L.J. Thrombocytopenia in Surgery and Neuraxial Anesthesia // Semin Thromb Hemost. 2020 Apr. Vol. 46. N 3. P. 245–55. DOI: 10.1055/s-0040-1702918.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Jacquenod P., Wallon G., Gazon M., Darnis B., Pradat P., Virlogeux V., et al. Incidence and Risk Factors of Coagulation Profile Derangement After Liver Surgery: Implications for the Use of Epidural Analgesia-A Retrospective Cohort Study // Anesth Analg. 2018. Vol. 126. N 4. Р. 1142–7. DOI: 10.1213/ane.0000000000002457.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Müller M.C., Arbous M.S., Spoelstra-de Man A.M., Vink R., Karakus A., Straat M., et al. Transfusion of fresh-frozen plasma in critically ill patients with a coagulopathy before invasive procedures: a randomized clinical trial (CME) // Transfusion. 2015. Vol. 55. N 1. Р. 26–35. DOI: 10.1111/trf.12750.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Koul A., Pant D., Rudravaram S., Sood J. Thoracic epidural analgesia in donor hepatectomy: An analysis // Liver Transpl. 2018 Feb. Vol. 24. N 2. P. 214-21. DOI: 10.1002/lt.24989.</mixed-citation></ref></ref-list></back></article>
