Regional Anesthesia and Acute Pain ManagementRegional Anesthesia and Acute Pain ManagementРегионарная анестезия и лечение острой боли1993-65082687-1394Eco-Vector62287710.17816/RA622877ReviewsНаучные обзорыReview ArticleEpidural use of glucocorticosteroids for treating radicular pain: narrative reviewЭпидуральное применение глюкокортикостероидов при лечении радикулярных болей: нарративный обзорhttps://orcid.org/0000-0002-1860-46096912-7740FedorovDmitrii A.ФёдоровДмитрий Андреевич
Russian Federation

anesthesiologist-resuscitator

врач анестезиолог-реаниматолог

293333666fedorov@gmail.comhttps://orcid.org/0000-0002-3162-62988640-9591KhinovkerVladimir V.ХиновкерВладимир Владимирович
Russian Federation

MD, Dr. Sci. (Med.)

д-р мед. наук

vhinov@hotmail.comhttps://orcid.org/0000-0002-3400-89896101-0578KoriachkinViktor A.КорячкинВиктор Анатольевич
Russian Federation

MD, Dr. Sci. (Med.), Professor

д-р мед. наук, профессор

vakoryachkin@mail.ruhttps://orcid.org/0000-0002-8860-94807440-1924KhinovkerEkaterina V.ХиновкерЕкатерина Владимировна
Russian Federation

anesthesiologist-resuscitator

врач анестезиолог-реаниматолог

khinov@mail.ruhttps://orcid.org/0000-0001-7709-5800KukharevAlexandr V.КухаревАлександр Васильевич
Russian Federation

neurosurgeon

нейрохирург

kuharevav@mail.ruFederal Siberian Scientific and Clinical CenterФедеральный Сибирский научно-клинический центрVoyno-Yasenetsky Krasnoyarsk State Medical UniversityКрасноярский государственный медицинский университет им. проф. В.Ф. Войно-ЯсенецкогоSt. Petersburg State Pediatric Medical UniversityСанкт-Петербургский государственный педиатрический медицинский университет01122023251220231742312413110202323112023Copyright ©; 2023, Eco-VectorCopyright ©; 2023, Эко-Вектор2023Eco-VectorЭко-Векторhttps://creativecommons.org/licenses/by-nc-nd/4.0/https://rjraap.com/1993-6508/article/view/622877

This review aimed to examine the history of the epidural use of glucocorticosteroids (GCS), perception of the safety of epidural administration of GCS, and examples of clinical use for the treatment of radiculopathies and radicular pain. The search for publications covered the period from February 2, 2023, to September 1, 2023, in PubMed, Medline, Cochrane Library, and the International Association for the Study of Pain. The search identified 306 studies, of which 243 were excluded because they described the pathophysiology and treatment of chronic pain syndromes other than neuropathic pain and epidural use of GCS. The remaining 63 publications were included in the review. The results of the analysis of the materials and publications revealed that the epidural use of GCS showed high effectiveness both as an independent method of treating radicular pain with neuropathy and as part of complex therapy. In some cases, the epidural use of GCS does not exclude neurosurgical intervention.

Целью обзора было описание истории, примеров клинического использования и безопасности эпидурального применения глюкокортикостероидов (ГКС) для лечения радикулопатий и радикулярных болей. Поиск публикаций производился с 02.02.2023 по 01.09.2023 в базах данных и электронных библиотеках PubMed (MEDLINE), Cochrane Library, а также International Association for the Study of Pain. В процессе поиска было обнаружено 306 исследований, из которых 243 работы исключены, поскольку описывали патофизиологические аспекты и лечение хронических болевых синдромов, не относящихся к нейропатической боли, и не включали эпидуральное применение ГКС. Оставшиеся 63 публикации составили основу обзора. Установлено, что эпидуральное применение ГКС имеет высокую эффективность как в качестве самостоятельного метода, так и в составе комплексной терапии при лечении радикулярных болей с нейропатическим компонентом. При этом эпидуральное применение ГКС не исключает проведения хирургического лечения.

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