Regional Anesthesia and Acute Pain ManagementRegional Anesthesia and Acute Pain ManagementРегионарная анестезия и лечение острой боли1993-65082687-1394Eco-Vector3626810.17816/RA36268ArticlesСтатьиResearch ArticleSystemic toxicity of local anesthetics in regional anesthesiaСистемная токсичность местных анестетиков при регионарной анестезииKoryachkinVictor A.КорячкинВиктор Анатольевичvakoryachkin@mail.ruGeras’kovE. VГераськовЕ. ВKazarinV. SКазаринВ. СLis’kovM. AЛиськовМ. АMokhannaM.МоханнаМ.Mal’tseM. PМальцеМ. ПMalevichG. MМалевичГ. МFSBI “P.P. Vreden Russian Scientific Research Institute of Traumatology and Orthopedics” MHC of RFФГБУ «Российский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена» МЗ РФ1509201593VOL 9, NO3 (2015)ТОМ 9, №3 (2015)455021072020Copyright ©; 2015, Eco-VectorCopyright ©; 2015, ООО "Эко-Вектор"2015Eco-VectorООО "Эко-Вектор"https://rjraap.com/1993-6508/article/view/36268

The article presents description of clinical case of lipid emulsion rescue during severe toxic reaction occurred in reply to accidental intravenous injection of local anesthetic solution. The article includes comprehensive data about epidemiology, clinical course and treatment of systemic toxicity of local anesthetics. It considers up-to-date understanding of mechanisms of antitoxic effect of lipid emulsion. The protocol of lipid emulsion rescue during systemic toxicity of local anesthetics is presented in the paper.

В статье описан клинический случай использования «липидной» реанимации при тяжелой токсической реакции в ответ на непреднамеренное внутрисосудистое введение раствора местного анестетика. Приводятся сведения об эпидемиологии, клинике и лечении системной токсичности местных анестетиков, рассмотрены современные представления о механизмах детоксикационного эффекта жировых эмульсий. Представлен протокол «липидной» реанимации при системной токсичности местных анестетиков.

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