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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Regional Anesthesia and Acute Pain Management</journal-id><journal-title-group><journal-title xml:lang="en">Regional Anesthesia and Acute Pain Management</journal-title><trans-title-group xml:lang="ru"><trans-title>Регионарная анестезия и лечение острой боли</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1993-6508</issn><issn publication-format="electronic">2687-1394</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">36255</article-id><article-id pub-id-type="doi">10.17816/RA36255</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Postoperative pain: the state of problem and current trends in postoperative analgesia</article-title><trans-title-group xml:lang="ru"><trans-title>Послеоперационная боль: состояние проблемы и современные тенденции послеоперационного обезболивания</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ovechkin</surname><given-names>Alexei M.</given-names></name><name xml:lang="ru"><surname>Овечкин</surname><given-names>Алексей Михайлович</given-names></name></name-alternatives><email>ovechkin_alexei@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">SBEI “I.M. Sechenov First Moscow State Medical University” of MHC of RF</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Первый московский государственный медицинский университет им. И.М. Сеченова» МЗ РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-06-15" publication-format="electronic"><day>15</day><month>06</month><year>2015</year></pub-date><volume>9</volume><issue>2</issue><issue-title xml:lang="en">VOL 9, NO2 (2015)</issue-title><issue-title xml:lang="ru">ТОМ 9, №2 (2015)</issue-title><fpage>29</fpage><lpage>39</lpage><history><date date-type="received" iso-8601-date="2020-07-21"><day>21</day><month>07</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, ООО "Эко-Вектор"</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2020-10-01"/></permissions><self-uri xlink:href="https://rjraap.com/1993-6508/article/view/36255">https://rjraap.com/1993-6508/article/view/36255</self-uri><abstract xml:lang="en"><p>The lecture is devoted to the problem of postoperative pain management that is actual at the moment despite of a valuable progress in methods of analgesia and analgesic drugs. The paper includes the results of foreign epidemiologic studies concerned adequacy of postoperative analgesia. Clinical implication and pathophysiology of postoperative pain is presented in details as well as goals of poatoperative analgesia and current approaches to postoperative pain management. Modern medications which effects are proved by evidence based medicine are considered in the presented lecture together with their characteristics and contradictions. The Concept of multimodal analgesia is also described. The author proposed several chemes of perioperative analgesia for various surgeries.</p></abstract><trans-abstract xml:lang="ru"><p>Лекция посвящена проблеме лечения послеоперационной боли, которая остается актуальной по сей день, несмотря на совершенствование методов анальгезии и обезболивающих препаратов. Приведены результаты зарубежных клинико-эпидемиологических исследований, касающихся качества послеоперационного обезболивания. В работе детально представлены клиническое значение и патофизиология послеоперационного болевого синдрома, а также задачи послеоперационного обезболивания и современные подходы к лечению послеоперационной боли. Описаны препараты, применение которых для послеоперационного обезболивания обосновано данными доказательной медицины, их особенности и противопоказания к их применению. Изложена концепция мультимодальной анальгезии как метода выбора в современной практике послеоперационного обезболивания. Приведены схемы периоперационного обезболивания при отдельных видах хирургических вмешательств.</p></trans-abstract><kwd-group xml:lang="en"><kwd>postoperative pain</kwd><kwd>perioperative analgesia</kwd><kwd>multimodal analgesia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>послеоперационный болевой синдром</kwd><kwd>обезболивание</kwd><kwd>периоперационная анальгезия</kwd><kwd>мультимодальная анальгезия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Harmer M., Davies К. The effect of education, assessment and a standardized prescription on postoperative pain management. The value of clinical audit in the establishment of acute pain services. Anaesthesia. 1998; 53: 424-430.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Neugebauer E., Hempel K., Sauerland S. The status of perioperative pain therapy in Germany. Results of a representative, anonymous survey of 1,000 surgical clinic. Pain Study Group. Chirurg. 1998; 69: 461-466.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Carr D., Goudas L. Acute pain. Lancet. 1999; 353: 2051-2058.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Dolin S., Cashman J., Bland J. Effectiveness of acute postoperative pain management: I. Evidence from published data. Br J. Anaesth, 2002; 89: 409-423.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Polomano R., Dunwoody C., Krenzischer D. Perspective on pain management in the 21st century. Pain Management Nurs. 2008; 9: 3-10.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Benhamou D., Berti M., Brodner G. Postoperative analgesic therapy observational survey (PATHOS): a practice pattern study in 7 central / southern European countries. Pain. 2008; 136: 134-141.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Gerbeshagen H., Aduckathil S., Van Wijck A., Peelen L., Kalkman C., Meissner W. Pain intensity on the first day after surgery. Anesthesiology. 2013; 118: 934-944.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Rodgers A., Walker N., Schug S. Reduction of postoperative mortality and morbidity with epidural or spinal anesthesia: results from overview of randomized trials. BMJ, 2000; 321: 1-12.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Acute Pain Management: Scientific Evidence. Australian and New Zeland College of Anaesthetists, 3-rd edition, Macintyre P., Scott D., Schug S. (eds), 2010.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Postoperative Pain Management - Good Clinical Practice. General recommendations and principles for successful pain management. Produced with the consultations with the Europeans Society of Regional Anaesthesia and Pain Therapy. Project chairman N. Rawal, 2005. 57S.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Kehlet H. Labat lecture 2005: surgical stress and postoperative outcome - from here to where? Reg. Anesth. Pain Med. 2006; 31: 47-52.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Gottschalk A., Sharma S., Ford J. The role of the perioperative period in recurrence after cancer surgery. Anesth. Analg. 2010; 110: 1636-1643.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Forrest J., Kamu F., Greer I. Ketorolack, diclofenac and ketoprofen are equally safe for pain relief after major surgery. Brit. J. Anaesth. 2002; 88: 227-233.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Schjerning Olsen A-M., Fosbol E., Lindhardsen J. Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study. Circulation. 2011; 123: 2226-2235.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Durrieu G., Oliver P., Bagheri H. Overview of adverse reactions to nefopam: an analysis of French pharmacovigilance database. Fund. Clin. Pharmacol. 2007; 21: 555-558.</mixed-citation></ref></ref-list></back></article>
