The article presents comparative assessment of hemodynamics in patients undergone operations on lower extremities under spinal anesthesia and peripheral nerve blockade. The study included 40 patients aged from 17 to 66 years. Patients in group 1 received spinal anesthesia, while patients in the 2nd group - sciatic nerve blockade or femoral nerve block. The hemodynamic parameters were measured and recorded according to Protocol of Anesthesia and Monitoring. Baseline parameter registrations were made in the operating room before surgery and then parameters were recorded every 5 min after onset of anesthesia and before the end of surgery and the transferring patient from the operating room to the ward. Patients undergone surgery under spinal anesthesia required obligatory continuous monitoring both during transferring to the ward and in immediate postoperative period. No hemodynamically substantial changes of blood pressure were observed during surgery performed under peripheral nerve block and complete stability of hemodynamics were noted in postoperative period.