Regional Anesthesia and Acute Pain ManagementRegional Anesthesia and Acute Pain ManagementРегионарная анестезия и лечение острой боли1993-65082687-1394Eco-Vector3618010.17816/RA36180ArticlesСтатьиReview ArticleClinical pharmacology of local anesthetics: classical concepts and new perspectives of applying in intensive therapyКлиническая фармакология местных анестетиков: классические представления и новые перспективы применения в интенсивной терапииOvechkinA. M.ОвечкинА. М.I. M. Sechenov Moscow Medical AcademyПервый московский государственный медицинский университет им. И. М. Сеченова1509201373VOL VII, NO3 (2013)ТОМ 7, №3 (2013)61521072020Copyright ©; 2013, Eco-VectorCopyright ©; 2013, ООО "Эко-Вектор"2013Eco-VectorООО "Эко-Вектор"https://rjraap.com/1993-6508/article/view/36180

The chemical characteristics and pharmacokinetics of different type of local anesthetics are considered in this overview. It also summarized up-to-date data concerning systemic effects of local anesthetics and potentiality for applying them widely in intensive therapy.

В обзоре изложены физико-химические и фармакокинетические свойства местных анестетиков, ответственных за эффективность методов регионарной анестезии, а также подробно рассмотрены все, известные на сегодняшний день, системные эффекты местных анестетиков, позволяющие более широко посмотреть на возможности их применения в интенсивной терапии.

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