Regional Anesthesia and Acute Pain ManagementRegional Anesthesia and Acute Pain ManagementРегионарная анестезия и лечение острой боли1993-65082687-1394Eco-Vector3610510.17816/RA36105ArticlesСтатьиResearch ArticlePharmacological Aspects of Local Anaesthetics in the ElderlyФармакологические особенности применения местных анестетиков у пожилых пациентовVeeringB.ВеерингБ.

Отделение анестезиологии Медицинского центра

Leiden UniversityЛейденский университет1503201151VOL 5, NO1 (2011)ТОМ 5, №1 (2011)495221072020Copyright ©; 2011, Eco-VectorCopyright ©; 2011, ООО "Эко-Вектор"2011Eco-VectorООО "Эко-Вектор"https://rjraap.com/1993-6508/article/view/36105

Ferrer-Brechner T. Spinal and epidural anesthesia in the elderly // Sem. Anesth. 1986; 54-61.Bromage P R. Epidural analgesia. Philadelphia // WB Saunders/ 1978; 40-42.Yoshikawa T. T. Physiology of aging: impact on pharmacology // Sem. Anesth. 1986; 8-13.Greenblatt D. J., Sellers E. M., Shader R. I. Drug disposition in old age // New Eng. J. Med. 1982; 306: 1081-1088.Wynne H. A., Cope L. H., Mutch E., Rawlins M. D., Woodhouse K. W., James O. F. W. The effect of age upon liver volume and apparent liver blood flow in healthy man // Hepatology. 1989; 9: 297-301.Wynne H. A., Goudevenos J., Rawlins M. D., James O. F. W., Adams P. C., Woudhouse K. W. Hepatic drug clearance: the effect of age using indocyanine green as a model compound // Brit. J. Clin. Pharm. 1990; 30: 634-637.Sato T., Miwa T., Tauchi H. Age changes in human liver of different races // Gerontologia. 1970; 16: 368-380.Veering B. T., Burm A. G. L., Van Kleef J. W., Hennis P. J., Spierdijk J. Epidural anesthesia with bupivacaine: effects of age on neural blockade and pharmacokinetics // Anesth. Analg. 1987; 66: 589-594.Simon M. J., Veering B. T., Stienstra R., van Kleef J. W., Burm A. G. The effects of age on neural blockade and hemodynamic changes after epidural anesthesia with ropivaca-ine // Anesth. Analg. 2002; 94: 1325-1330.Simon M. J., Veering B. T., Stienstra R., van Kleef J. W., Burm A. G. Effect of age on the clinical profile and systemic absorption and disposition of levobupivacaine after epidural administration // Br. J. Anaesth. 2004; 93: 512-520.Racle J. P., Benkhadra A., Poy J. Y., Gteizal B. Spinal analgesia with hyperbaric bupivacaine: influence of age // Br. J. Ana-esth. 1988; 60: 508-514.Veering B. T., Burm A. G. L., Spierdijk J. Spinal anaesthesia with hyperbaric bupivacaine: effects of age on neural blockade and pharmacokinetics // Br. J. Anaesth. 1988; 60: 187194.Pitkanen M., Haapaniemi L., Tuominen M., Rosenberg P H. Influence of age on spinal anaesthesia with isobaric 0.5% bupivacaine // Br. J. Anaesth. 1984; 56: 279-284.Veering B. T., Burm A. G. L., Van Kleef J. W., Hennis P. J., Spierdijk J. Spinal anesthesia with glucose-free bupivacaine: effects of age on neural blockade and pharmacokinetics // Analg. Anesth. 1987; 66: 965-970.Snoeck M. M., Vree T. B., Gielen M. J. et al. Steady state bupivacaine plasma concentrations and safety of a femoral '3-in-l' nerve block with bupivacaine in patients over 80 years of age // Int. J. Clin. Pharmacol. Ther. 2003; 41: 107-131.Paqueron X., Boccara G., Bendahou M. et al. Brachial plexus nerve block exhibits prolonged duration in the elderly // Anesthesiology. 2002; 92: 1330-1334.Dorfman L. J., Bosley T. M. Age related changes in peripheral and central nerve conduction in man // Neurology. 1979; 29: 38-44.Abemathy D. R., Greenblatt D. J. Impairment of lidocaine clearance in elderly male subjects // J. Cardiovasc. Pharmac. 1983; 5: 1093-1096.Cusson J., Nattel S., Matthews C., Talajic M., Lawand S. Age-dependent lignocaine disposition in patients with acute myocardial infarction // Clin. Pharmacol. Ther. 1985; 37: 381-386.Bowdle T. A., Freund P. R., Slattery J. T. Age dependent lidocaine pharmacokinetics during lumbar peridural anaesthesia with lidocaine hydrocarbonate or lidocaine hydrochloride // Reg. Anesth. 1986; 11: 123-127.Simon M. J. G., Veering B. T., Burm A. G. L., Stienstra R., Van Kleef J. W. The effect of age on the the systemic absorption and disposition of ropivacaine following epidural anesthesia // Anesth. Analg. 2006; 101: 276-282.Veering B. T., Burm A. G. L., Gladines M. P R. R., Spierdijk J. Age does not influence the serum protein binding of bupi-vacaine // Br. J. Clin. Pharmac. 1991; 32: 501-503.Mather L. E., Thomas J. Bupivacaine binding to plasma protein fractions // J. Pharm. Pharmacol. 1978; 30: 653-654.Veering B. T., Burm A. G. L., Vietter A. A., van den Heuvel R. P M., Onkenhout W., Spierdijk J. The effect of age on the systemic absorption and systemic disposition of bupivacaine after epidural administration // Clin. Pharmacokinet. 1992; 22: 75-84.Burm A. G. L., Van Kleef J. W., Vermeulen N. P E., Olthof G., Breimer D. D., Spierdijk J. Pharmacokinetics of lidocaine and bupivacaine following subarachnoid administration in surgical patients: simultaneous investigation of absorption and disposition kinetics using stable isotopes // Anesthesiology. 1988; 69: 584-592.Simon M. J. G., Veering B. T., Burm A. G. L., Stienstra R., Van Kleef J. W. The effect of age on the clinical profile and the systemic absorption and disposition of levobupivacaine following epidural anaesthesia // Br. J. Anaesth. 2004; 93: 512-520.Veering B. T., Burm A. G. L., Vietter A. A., Van den Hoeven R. A. M., Spierdijk J. The effect of age on systemic absorption and systemic disposition of bupivacaine after subarachnoid administration // Anesthesiology. 1991; 74: 250-257.Olofsen E., Burm A. G. L., Simon M., Veering B. T., van Kleef J. Dahan A. Population Pharmacokinetic-Pharmacodynamic Modeling of Epidural Anesthesia // Anesthesiology. 2008; 109: 664-674.