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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Regional Anesthesia and Acute Pain Management</journal-id><journal-title-group><journal-title xml:lang="en">Regional Anesthesia and Acute Pain Management</journal-title><trans-title-group xml:lang="ru"><trans-title>Регионарная анестезия и лечение острой боли</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1993-6508</issn><issn publication-format="electronic">2687-1394</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">108819</article-id><article-id pub-id-type="doi">10.17816/RA108819</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Original study articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Comparative analysis of monolateral and bilateral spinal anesthesia</article-title><trans-title-group xml:lang="ru"><trans-title>Сравнительный анализ монолатеральной и билатеральной спинальной анестезии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3947-1339</contrib-id><name-alternatives><name xml:lang="en"><surname>Filimonov</surname><given-names>Roman V.</given-names></name><name xml:lang="ru"><surname>Филимонов</surname><given-names>Роман Владимирович</given-names></name></name-alternatives><address><country country="UA">Ukraine</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.), assistant</p></bio><bio xml:lang="ru"><p>к.м.н., ассистент кафедры анестезиологии и интенсивной терапии</p></bio><email>roman.filimonow@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6391-8300</contrib-id><name-alternatives><name xml:lang="en"><surname>Gritsenko</surname><given-names>Sergey N.</given-names></name><name xml:lang="ru"><surname>Гриценко</surname><given-names>Сергей Николаевич</given-names></name></name-alternatives><address><country country="UA">Ukraine</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>gritsenko45@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2977-1223</contrib-id><name-alternatives><name xml:lang="en"><surname>Filimonova</surname><given-names>Inna V.</given-names></name><name xml:lang="ru"><surname>Филимонова</surname><given-names>Инна Владимировна</given-names></name></name-alternatives><address><country country="UA">Ukraine</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>к.м.н.</p></bio><email>filimonovainna1975@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kobelyatskyy</surname><given-names>Yuriy Yu.</given-names></name><name xml:lang="ru"><surname>Кобеляцкий</surname><given-names>Юрий Юрьевич</given-names></name></name-alternatives><address><country country="UA">Ukraine</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Med.), Professor</p></bio><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><email>kobeliatsky@ukr.net</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Zaporozhye Medical Academy of Postgraduate Education</institution></aff><aff><institution xml:lang="ru">Запорожская медицинская академия последипломного образования</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Dnepropetrovsk Medical Academy</institution></aff><aff><institution xml:lang="ru">Днепропетровская медицинская академия</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2021</year></pub-date><volume>15</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>237</fpage><lpage>244</lpage><history><date date-type="received" iso-8601-date="2022-06-18"><day>18</day><month>06</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-06-18"><day>18</day><month>06</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, ООО "Эко-Вектор"</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder></permissions><self-uri xlink:href="https://rjraap.com/1993-6508/article/view/108819">https://rjraap.com/1993-6508/article/view/108819</self-uri><abstract xml:lang="en"><p><bold><italic>AIM</italic></bold><italic>:</italic> This study aimed to improve the treatment results of patients with diabetic foot syndrome by substantiating the optimal type of spinal anesthesia during foot surgery.</p> <p><bold><italic>MATERIALS</italic></bold> <bold><italic>AND</italic></bold> <bold><italic>METHODS</italic></bold><italic>:</italic> Sixty-four patients undergoing purulent surgery were examined and group as follows: Group 1 – patients operated on under monolateral (unilateral) spinal anesthesia and Group 2 – patients operated on under conditions of bilateral (traditional) spinal anesthesia.</p> <p><bold><italic>RESEARCH</italic></bold> <bold><italic>METHODS</italic></bold><italic>:</italic> Assessment of the level and intensity of pain and the level of catecholamines in urine was conducted in the first postoperative day. Cardiovascular system indicators and the temperature of the skin of the leg during anesthesia were monitored, and the Doppler scanning of peripheral circulation in the foot was performed.</p> <p><bold><italic>RESULTS</italic></bold><italic>:</italic> Pain sensitivity during lower limb movement was 20% less pronounced in group 1 than in group 2. A 4.4% decrease in heart rate, a 4.7% decrease in saturation level recorded 20 minutes after the onset of anesthesia, and a 9.8% decrease in mean arterial pressure were observed in group 2. In both groups, systolic blood pressure in the toe increased by 18% after anesthesia, and the temperature of the skin on the lateral surface of the leg increased by 3%. Adrenaline concentration in the daily portion of urine in group 2 was 34.4% higher than that in group 1 in the next postoperative day.</p> <p><bold><italic>CONCLUSIONS</italic></bold><italic>: </italic>The general condition of patients during anesthesia was more stable in group 1 than in group 2. After anesthesia, improved peripheral hemodynamics in the operated limb was noted. Compared with traditional spinal anesthesia, monolateral spinal anesthesia has a positive effect on the stress response of the patient’s body to surgical intervention.</p></abstract><trans-abstract xml:lang="ru"><p><bold><italic>Цель</italic></bold><italic>. </italic>Улучшить результаты лечения больных с синдромом диабетической стопы путём обоснования оптимального вида спинальной анестезии при хирургическом вмешательстве на стопе.</p> <p><bold><italic>Материалы и методы</italic></bold><italic>.</italic> Обследовано 64 больных, проходивших лечение в отделении гнойной хирургии. Группы больных: 1-я группа – больные, оперированные в условиях монолатеральной (односторонней) спинальной анестезии; 2-я группа – больные, оперированные в условиях билатеральной (традиционной) спинальной анестезии. Методы – оценка уровня и интенсивности боли, уровня катехоламинов в моче в первые послеоперационные сутки, мониторинг показателей сердечно-сосудистой системы, допплеровского сканирования периферического кровообращения в стопе, температуры кожных покровов голени во время анестезии и статистические анализы.</p> <p><bold><italic>Результаты</italic></bold><italic>.</italic> В 1-й группе болевая чувствительность при движении нижней конечностью на 20% меньше выражена, чем во 2-й группе. Во 2-й группе частота сердечных сокращений урежалась на 4,4%. Зафиксировано снижение уровня сатурации через 20 мин после начала анестезии во 2-й группе на 4,7%. Среднее артериальное давление во 2-й группе снизилось в ходе анестезии на 9,8%. В обеих группах систолическое артериальное давление в пальце стопы повысилось на 18% после выполнения анестезии, а температура кожи на латеральной поверхности голени – на 3%. Концентрация адреналина в суточной порции мочи в ближайшие послеоперационные сутки во 2-й группе на 34,4% выше, чем в 1-й группе.</p> <p><bold><italic>Выводы</italic></bold><italic>.</italic> В ходе анестезии показатели АД, ЧСС и сатурации в 1-й группе не изменялись в сравнении с исходными (до анестезии). После анестезии отмечено улучшение периферической гемодинамики в оперированной конечности. Монолатеральная спинальная анестезия, по сравнению с традиционной спинальной анестезией, положительно влияет на стресс-реакцию организма больного на хирургическое вмешательство.</p></trans-abstract><kwd-group xml:lang="en"><kwd>diabetic foot syndrome</kwd><kwd>regional anesthesia</kwd><kwd>monolateral spinal anesthesia</kwd><kwd>bilateral spinal anesthesia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>синдром диабетической стопы</kwd><kwd>регионарная анестезия</kwd><kwd>монолатеральная спинальная анестезия</kwd><kwd>билатеральная спинальная анестезия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Byshovets SN. Anaesthetic component of the fast track surgery strategy:spinal anaesthesia with bupivacaine, prolonged by buprenorphine. 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