Current Medicinal ChemistryCurrent Medicinal ChemistryCurrent Medicinal Chemistry0929-86731875-533XBentham Science64516210.2174/092986733105230911112507Anti-Infectives and Infectious DiseasesResearch ArticleNovel and Latest Computational Routes in the Design and Development of Anticancer DrugsKamalMohammadinfo@benthamscience.netAkhtarSalmaninfo@benthamscience.netInstitutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, Sichuan UniversityDepartment of Bioengineering, Faculty of Engineering & Information Technology,, Integral University,0102202431555255307012025Copyright ©; 2024, Bentham Science Publishers2024Bentham Science Publishershttps://rjraap.com/0929-8673/article/view/645162[Talluri, S.; Kamal, M.A.; Malla, R.R. Novel computational methods for cancer drug design. Curr. Med. Chem., 2024, 31(5), 554-572.][Ghosh, A.; Ghosh, D.; Mukerjee, N. et al. The efficient activity of glabridin and its derivatives against EGFR-mediated inhibition of breast cancer. Curr. Med. Chem., 2024, 31(5), 573-594.][Shah, A.A.; Ahmad, S.; Yadav, M.K.; Raza, K.; Kamal, M.A.; Akhtar, S. Structure-based virtual screening, molecular docking, molecular dynamics simulation, and metabolic reactivity studies of quinazoline derivatives for their anti-EGFR activity against tumor angiogenesis. Curr. Med. Chem., 2024, 31(5), 595-619.][Alam, S.; Verma, S.; Fatima, K.; Luqman, S.; Srivastava, S.K.; Khan, F. Pharmacophore & QSAR guided design, synthesis, pharmacokinetics, and in vitro evaluation of curcumin analogs for anticancer activity. Curr. Med. Chem., 2024, 31(5), 620-639.][Ahmad, S. lshammari, Q.T.; Rafi, Z. et al. Generation of autoantibodies in metal-catalyzed oxidatively damaged DNA in various cancer subjects. Curr. Med. Chem., 2024, 31(5), 640-648.][Mirza, Z. Integrated high-throughput transcriptomic data identifies survivin as a potential breast cancer therapeutic biomarker. Curr. Med. Chem., 2024, 31(5), 649-663.]